Table 1.
Baseline characteristics of PD stratified by RBD
| PD with RBD | PD without RBD | P value | |
|---|---|---|---|
| (N = 136) | (N = 214) | ||
| Age, years | 61.22 ± 9.44 | 60.42 ± 9.88 | 0.447 |
| Males, n(%) | 92(67.6%) | 137(64.0%) | 0.564 |
| Education, year | 15.61 ± 2.91 | 15.57 ± 2.97 | 0.890 |
| ApoE4(%) | 23.40% | 24.50% | 0.893 |
| RBD | 7.04 ± 1.91 | 2.53 ± 1.17 | < 0.001* |
| Disease duration (months) | 7.51 ± 6.69 | 7.35 ± 6.29 | 0.816 |
| Hoehn and Yahr Stage | 1.57 ± 0.49 | 1.51 ± 0.52 | 0.289 |
| UPDRS part III | 21.58 ± 9.41 | 19.63 ± 8.39 | 0.044* |
| UPDRS1.1 Cognition, N (% positive) | 39(28.7%) | 46(21.5%) | 0.159 |
| MoCA | 26.98 ± 2.40 | 27.32 ± 2.21 | 0.170 |
| UPSIT Total | 21.60 ± 8.39 | 22.33 ± 7.96 | 0.411 |
| Geriatric Depression Scale | 5.39 ± 1.94 | 5.10 ± 1.37 | 0.065 |
| Total STAI | 93.58 ± 8.49 | 93.33 ± 7.58 | 0.771 |
Results are mean ± (SD). P value was assessed using two-tailed Student t test for each variable except gender, ApoE4 and UPDRS1.1, where chi-square (χ2) test was performed. *P value statistically significant. The age, education, ApoE4, disease duration, Hoehn and Yahr Stage, UPDRS1.1 Cognition, MoCA, UPSIT Total, depression and total STAI had no difference between two groups. However, the PD with RBD group had relative greater UPDRS part III
Abbreviations: PD Parkinsonr’s disease, RBD Rapid eye movement sleep behavioral disorder, ApoE4 Apolipoprotein E ɛ4, UPDRS Unified Parkinson’s Disease Rating Scale, MoCA Montreal Cognitive Assessment, UPSIT University of Pennsylvania Smell Identification Test, STAI State Trait Anxiety Inventory