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ER STRESS RESPONSES LEADING TO CELL SURVIVAL OR CELL DEATH
| ER Stress | Response |
|---|---|
| Activation of IRE1/2 kinase/endonuclease | |
| Induction of membrane biosynthesis | survival |
| Induction of ER protein chaperones | survival |
| Induction of GADDI53/CHOP | death |
| Activation of eIF-2 kinase | |
| Inhibition of translation | survival |
| Induction of cell death | death |
