Table 2.
Study | Year | Study type | Intervention | Treatment regimens | No. of patients |
---|---|---|---|---|---|
Brahmer | 2015 | Phase III | Nivolumab |
3mg/kg ivgtt q2w |
135 |
Docetaxel | 75mg/m2 ivgtt q3w | 137 | |||
Borghaei | 2015 | Phase III | Nivolumab |
3mg/kg ivgtt q2w |
292 |
Docetaxel | 75mg/m2 ivgtt q3w | 290 | |||
Pembrolizumab |
2mg/kg ivgtt q3w |
344 |
|||
Herbst | 2015 | Phase III | Pembrolizumab |
10mg/kg ivgtt q3w |
346 |
Docetaxel | 75mg/m2 ivgtt q3w | 343 | |||
Fehrenbacher | 2016 | Phase II | Atezolizumab |
1200mg ivgtt q3w |
144 |
Docetaxel | 75mg/m2 ivgtt q3w | 143 | |||
Rittmeyer | 2017 | Phase III | Atezolizumab |
1200mg ivgtt q3w |
425 |
Docetaxel | 75mg/m2 ivgtt q3w | 425 |