Fig. 1.

Schematic of study design. Net changes in gene expression induced by IL-4 in mSBC and hPBBC were calculated following creation of two lists of genes by subtraction of both references, Pre and Ctrl, to IL-4, i.e., the IL-4 – Pre and IL-4 – Ctrl lists, expressed as log₂ratios. For entities that took equal sign in both lists, net change was the smaller of the two values in absolute terms, positive (A and B) or negative (D and E). For entities that took opposite sign in both lists (C and F), net change could not be calculated and these entities were excluded. Pre, sample prior to culture; Ctrl and IL-4, samples cultured in parallel for 18 h with nothing and IL-4, respectively.