Fig. 5.

Inhibition of NOX in BE(2)-C cells by different indicated concentrations of NOX inhibitor VAS2870 leads to a lower intracellular H₂O₂-level and decreased acetylation of SMC3. Immuno-blot results (A) and their respective quantification (B) are shown. The solvent (DMSO) control is indicated with a hyphen sign. Data here are the average ± standard deviation of five independent repeats. Statistical significance was determined by Student's t-test. *: p-value = 0.019 and ***: p-value = 0.0002.