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. 2018 Sep 27;20:68–74. doi: 10.1016/j.redox.2018.09.018

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4 — Markers of oxidative stress in the WT and Sod1^-/- mice treated with CDN1163 or vehicle. CDN1163 reduces the state-1 and state-2 complex 1-linked (glutamate malate) mitochondrial peroxide production (A) in the gastrocnemius muscles and the F₂-isoprostanes as a marker of lipid peroxidation (B) in the quadriceps muscles in the in the Sod1^-/- mice when compared to the vehicle treatment. Values are expressed as Mean ± SEM (WT-DMSO; n = 4, WT-CDN1163; n = 6, Sod1^-/--DMSO; n = 5, Sod1^-/--CDN1163; n = 5).; One-way ANOVA. * P ≤ 0.05.