REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
ADI-15878	(Bornholdt et al., 2016b); Mapp Biopharmaceutical	N/A
ADI-16061	(Bornholdt et al., 2016b); Mapp Biopharmaceutical	N/A
c13C6	Mapp Biopharmaceutical	N/A
BDBV289	(Flyak et al., 2016); J.E. Crowe	N/A
Chemicals, Peptides, and Recombinant Proteins
FreeStyle 293 expression medium	Thermo Fisher	Cat no. 12338018
ExpiCHO expression medium	Thermo Fisher	Cat no. A2910001
ExpiCHO feed	Thermo Fisher	Cat no. A2910002
Opti-MEM	Thermo Fisher	Cat no. 31985070
EBOV GPΔMuc-Makona variant	This study	N/A
BDBV GPΔMuc	This study	N/A
n-Dodecyl-beta-Maltoside	Anatrace	Part no. D310S
A8–35 amphipole	Anatrace	Part no. A835
Deposited Data
ADI-15878 Fab complex with EBOV GPΔMuc-Makona variant cryo-EM map	This paper	EMDB; EMD-8935
ADI-15878 Fab complex with BDBV GPΔMuc variant cryo-EM map	This paper	EMDB; EMD-8936
ADI-15878 Fab complex with EBOV GPΔMuc-Makona variant model	This paper	PDB; 6DZL
ADI-15878 Fab complex with BDBV GPΔMuc model	This paper	PDB; 6DZM
Unliganded ADI-15878 Fab crystal structure	This paper	PDB; 6DZN
Experimental Models: Cell Lines
293-FreeStyle	Thermo Fisher	R79007
ExpiCHO	Thermo Fisher	A29127
Oligonucleotides
pPPI4 Sequencing primer For: AGCGGCAGAAGAAGATGCAGGCAGC	This study	N/A
BGH_Rev Sequencing primer: CCTCGACTGTGCCTTCTA	Eton Bioscience	N/A
AbVec Sequencing primer For: AGTCTATAGGCCCACCCCCT	This study	N/A
AbVec Sequencing primer Rev: AACCATTATAAGCTGCAATAAACAA	This study	N/A
Recombinant DNA
pPPI4-EBOV GPΔMuc Makona variant-Ek-ddStrep	This study	N/A
pPPI4-BDBV GPΔMuc-Ek-ddStrep	This study	N/A
AbVec-ADI-15878 HC Fab	This study	N/A
AbVec-ADI-16061 HC Fab	This study	N/A
AbVec-BDBV289 HC Fab	This study	N/A
AbVec-ADI-15878 LC	This study	N/A
AbVec-ADI-16061 LC	This study	N/A
AbVec-BDBV289 LC	This study	N/A
Software and Algorithms
COOT	Emsley et al., 2010	http://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot
Phenix	Adams et al., 2010	https://www.phenix-online.org
HKL2000	Otwinowski and Minor, 1997	http://www.hkl-xray.com/
MotionCor2	Zheng et al., 2017	http://msg.ucsf.edu/em/software/motioncor2.html
GCTF	Zhang, 2016
DoG Picker	Voss et al., 2009	http://emg.nysbc.org/redmine/projects/software/wiki/DoGpicker
Relion 2.0	Scheres, 2012	http://www2.mrc-lmb.cam.ac.uk/relion/index.php?title=Main_Page
UCSF Chimera	Pettersen et al., 2004	https://www.cgl.ucsf.edu/chimera/
Rosetta	DiMaio et al., 2015	https://www.rosettacommons.org/
Swiss Modeler	Biasini et al., 2014	https://swissmodel.expasy.org/
Phaser	McCoy et al., 2007	http://www.ccp4.ac.uk/html/phaser.html
BUSTER	Bricogne et al., 2017	https://www.globalphasing.com/buster/
Refmac5	Murshudov et al., 2011	http://www.ccp4.ac.uk/html/refmac5.html
EMRinger	Barad et al., 2015	http://emringer.com
Molprobity	Chen et al., 2010	http://molprobity.biochem.duke.edu
PDBcare	Lütteke and von der Lieth, 2004	www.glycosciences.de/tools/pdb-care/
Privateer	Agirre et al., 2015	www.ccp4.ac.uk/html/privateer.html
Other
Titan Krios 300kV electron microscope	Thermo Fisher	https://www.fei.com/
Talos Arctica 200kV electron microscope	Thermo Fisher	https://www.fei.com/
K2 Summit camera	Gatan	http://www.gatan.com
Vitrobot	Thermo Fisher	https://www.fei.com/
Gatan Solarus 950 Plasma system	Gatan	http://www.gatan.com