Table 1.
Baseline characteristics of the total population by coronary risk before adjusting for propensity score
| <5% | SDiffa | SDiffa | ≥5%‐7.4% | SDiffa | SDiffa | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Statin nonusers | Statin users MPR < 70% | Statin users MPR ≥ 70% | Statin nonusers | Statin users MPR < 70% | Statin users MPR ≥ 70% | ||||
| Age, mean (SD) years | 48.50 (9.75) | 55.23 (9.97) | 57.24 (9.63) | −0.68 | −0.9 | 58.62 (8.46) | 58.09 (8.53) | 59.50 (7.98) | 0.06 | −0.11 |
| Sex (% women) | 59.18 | 71.40 | 74.79 | −0.26 | −0.34 | 26.92 | 41.47 | 49.39 | −0.31 | −0.48 |
| High‐risk alcohol intake (%) | 2.65 | 2.26 | 1.79 | 0.02 | 0.06 | 6.73 | 4.47 | 4.03 | 0.1 | 0.12 |
| Smokers (%) | 31.13 | 23.17 | 19.72 | 0.18 | 0.26 | 51.29 | 39.60 | 32.29 | 0.24 | 0.39 |
| Diabetes (%) | 2.06 | 6.26 | 8.87 | −0.21 | −0.3 | 13.33 | 21.10 | 26.79 | −0.21 | −0.34 |
| Hypertension (%) | 13.08 | 29.09 | 39.00 | −0.4 | −0.62 | 33.47 | 43.15 | 49.44 | −0.2 | −0.33 |
| Dyslipidemia (%) | 11.62 | 57.28 | 72.82 | −1.1 | −1.58 | 23.10 | 60.38 | 71.45 | −0.82 | −1.11 |
| Obesity (%) | 30.04 | 39.55 | 40.71 | −0.2 | −0.22 | 43.49 | 45.88 | 49.27 | −0.05 | −0.12 |
| Chronic kidney disease (%) | 0.22 | 0.79 | 1.04 | −0.08 | −0.1 | 0.64 | 0.84 | 1.13 | −0.02 | −0.05 |
| Blood pressure | ||||||||||
| Systolic, mean (SD), mm Hg | 125.19 (15.06) | 128.00(14.54) | 128.71(14.59) | −0.19 | −0.24 | 138.20(15.67) | 136.94(15.75) | 136.93(16.18) | 0.08 | 0.08 |
| Diastolic, mean (SD), mm Hg | 76.63(9.53) | 77.65(9.06) | 77.63(8.96) | −0.11 | −0.11 | 81.88(10.06) | 81.25(9.74) | 80.84(9.75) | 0.06 | 0.1 |
| Total cholesterol, mean (SD), mmol/L | 5.19(0.88) | 6.54(1.10) | 6.81(1.04) | −1.36 | −1.68 | 5.64(0.92) | 6.62(1.11) | 6.75(1.04) | −0.96 | −1.13 |
| Total cholesterol, mean (SD), mg/dl | 200.79(34.12) | 253.01(42.48) | 263.17(40.08) | −1.36 | −1.68 | 218.06(35.68) | 256.10(43.08) | 260.93(40.06) | −0.96 | −1.13 |
| LDL‐cholesterol,mean (SD), mmol/L | 3.26(0.79) | 4.37(0.97) | 4.55(0.92) | −1.25 | −1.5 | 3.48(0.83) | 4.36(0.99) | 4.48(0.94) | −0.96 | −1.12 |
| LDL cholesterol, mean (SD), mg/dl | 126.02(30.70) | 168.93(37.59) | 175.96(35.60) | −1.25 | −1.50 | 134.39(32.25) | 168.58(38.37) | 173.06(36.48) | −0.96 | −1.13 |
| HDL cholesterol, mean (SD), mmol/L | 1.52(0.40) | 1.58(0.38) | 1.61(0.37) | −0.15 | −0.22 | 1.26(0.30) | 1.32(0.30) | 1.34(0.29) | −0.2 | −0.29 |
| HDL cholesterol, mean (SD), mg/dl | 58.89(15.33) | 61.11(14.58) | 62.10(14.26) | −0.15 | −0.22 | 48.62(11.77) | 51.01(11.73) | 52.00(11.26) | −0.20 | −0.29 |
| Serum triglycerides, mmol/L | 1.21(0.68) | 1.57(1.06) | 1.60(1.09) | −0.41 | −0.43 | 1.52(0.91) | 1.99(1.45) | 1.94(1.19) | −0.39 | −0.40 |
| Serum triglycerides, mg/dl | 106.76(60.28) | 139.41(93.58) | 141.48(96.40) | −0.41 | −0.43 | 134.20(80.26) | 175.89(128.13) | 171.69(105.82) | −0.39 | −0.40 |
| Glucose, mmol/L | 5.08(0.95) | 5.43(1.40) | 5.59(1.61) | −0.29 | −0.39 | 5.76(1.58) | 6.19(2.19) | º6.43(2.25) | −0.23 | −0.34 |
| Glucose, mg/dl | 91.43(17.02) | 97.77(25.26) | 100.57(28.9) | −0.29 | −0.39 | 103.67(28.39) | 111.5(39.5) | 115.67(40.52) | −0.23 | −0.34 |
| Body mass index, kg/m2 | 27.26(5.30) | 28.69(5.31) | 28.85(5.25) | −0.27 | −0.3 | 29.27(5.32) | 29.64(5.36) | 29.92(5.19) | −0.07 | −0.12 |
| 10‐year CHD risk, mean (SD) | 1.97(1.22) | 2.88(1.14) | 3.06(1.09) | −0.77 | −0.95 | 6.04(0.71) | 6.07(0.70) | 6.15(0.72) | −0.05 | −0.15 |
| ≥7.5‐9.9% | SDiffb | SDiffb | ≥10‐19.9% | SDiffa | SDiffa | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Statin nonusers | Statin users MPR<70 | Statin users MPR≥70 | Statin nonusers | Statin users MPR<70 | Statin users MPR≥70 | ||||
| Age, mean (SD) years | 61.83(7.71) | 59.73(7.76) | 60.83(7.66) | 0.27 | 0.13 | 65.04(6.74) | 62.45(7.06) | 63.40(6.87) | 0.38 | 0.24 |
| Sex (% women) | 16.26 | 27.43 | 29.17 | −0.27 | −0.31 | 9.32 | 15.60 | 17.17 | −0.19 | −0.23 |
| High‐risk alcohol intake (%) | 8.17 | 7.17 | 6.62 | 0.04 | 0.06 | 8.54 | 10.56 | 7.28 | −0.07 | 0.05 |
| Smokers (%) | 60.65 | 54.40 | 44.16 | 0.13 | 0.33 | 73.00 | 67.03 | 62.06 | 0.13 | 0.24 |
| Diabetes (%) | 21.88 | 31.75 | 37.73 | −0.22 | −0.35 | 31.81 | 43.67 | 50.65 | −0.25 | −0.39 |
| Hypertension (%) | 39.99 | 46.18 | 53.95 | −0.13 | −0.28 | 46.07 | 52.72 | 61.00 | −0.13 | −0.3 |
| Dyslipidemia (%) | 25.24 | 61.84 | 71.00 | −0.79 | −1.03 | 27.62 | 61.98 | 69.81 | −0.74 | −0.93 |
| Obesity, No (%) | 45.14 | 44.89 | 47.85 | 0.01 | −0.05 | 47.25 | 46.11 | 49.60 | 0.02 | −0.05 |
| Chronic kidney disease (%) | 0.92 | 0.97 | 1.01 | −0.01 | −0.01 | 1.22 | 1.76 | 2.02 | −0.04 | −0.06 |
| Blood pressure | ||||||||||
| Systolic, mean (SD), mm Hg | 141.01(15.87) | 139.43(16.40) | 139.48(16.61) | 0.1 | 0.09 | 144.82(15.76) | 143.70(16.24) | 143.69(16.23) | 0.07 | 0.07 |
| Diastolic, mean (SD), mm Hg | 82.31(10.20) | 81.83(10.13) | 81.82(9.80) | 0.05 | 0.05 | 82.66(10.09) | 82.57(10.17) | 82.06(10.09) | 0.01 | 0.06 |
| Total cholesterol, mean (SD), mmol/L | 5.68(0.94) | 6.62(1.10) | 6.66(1.05) | −0.92 | −0.99 | 5.76(0.96) | 6.58(1.00) | 6.61(1.02) | −0.83 | −0.85 |
| Total cholesterol, mean (SD), mg/dl | 219.62(36.45) | 256.04(42.65) | 257.61(40.48) | −0.92 | −0.99 | 222.91(37.15) | 254.63(38.81) | 255.50(39.55) | −0.83 | −0.85 |
| LDL cholesterol, mean (SD), mmol/L | 3.48(0.84) | 4.37(0.97) | 4.39(0.91) | −0.99 | −1.04 | 3.50(0.84) | 4.31(0.93) | 4.33(0.88) | −0.92 | −0.97 |
| LDL cholesterol, mean (SD), mg/dl | 134.53(32.43) | 169.15(37.42) | 169.69(35.27) | −0.99 | −1.04 | 135.31(32.45) | 166.75(35.77) | 167.61(33.90) | −0.92 | −0.97 |
| HDL cholesterol, mean (SD), mmol/L | 1.22(0.29) | 1.25(0.28) | 1.26(0.26) | −0.14 | −0.17 | 1.15(0.26) | 1.18(0.26) | 1.18(0.25) | −0.11 | −0.14 |
| HDL cholesterol, mean (SD), mg/dl | 47.00(11.25) | 48.52(10.93) | 48.84(10.10) | −0.14 | −0.17 | 44.48(9.97) | 45.55(10.10) | 45.81(9.56) | −0.11 | −0.14 |
| Serum triglycerides, mmol/L | 1.58(0.96) | 2.08(1.34) | 2.12(1.48) | −0.42 | −0.43 | 1.66(1.06) | 2.23(1.58) | 2.24(1.62) | −0.42 | −0.42 |
| Serum triglycerides, mg/dl | 140.16(85.39) | 183.85(119.07) | 187.80(131.23) | −0.42 | −0.43 | 147.38(94.12) | 197.83(140.35) | 198.74(143.38) | −0.42 | −0.42 |
| Glucose, mmol/L | 6.12(1.94) | 6.63(2.44) | 6.96(2.7) | −0.23 | −0.36 | 6.54(2.22) | 7.12(2.6) | 7.63(3.19) | −0.24 | −0.40 |
| Glucose, mg/dl | 110.09(34.86 | 119.33(43.95) | 125.21(48.6) | −0.23 | −0.36 | 117.65(40.04) | 128.21(47.12) | 137.41(57.38) | −0.24 | −0.40 |
| Body Mass Index, kg/m2 | 29.48(5.23) | 29.61(5.13) | 29.88(5.03) | −0.02 | −0.08 | 29.67 5.14 | 29.67 4.92 | 29.85 4.81 | 0.00 | −0.04 |
| 10‐year CHD risk, mean (SD) | 8.58(0.70) | 8.62(0.71) | 8.67(0.70) | −0.06 | −0.12 | 12.90(2.44) | 13.18(2.52) | 13.44(2.60) | −0.11 | −0.21 |
a
SDiff: standardized differences with respect to nonusers.
SDiff: standardized differences with respect to nonusers.