Table 2.
Baseline characteristics of the total population by coronary risk after adjusting for propensity score
| <5% | SDiffa | SDiffa | ≥5‐7.4% | SDiffa | SDiffa | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Statin nonusers | Statin users MPR < 70% | Statin users MPR ≥ 70% | Statin nonusers | Statin users MPR<70% | Statin users MPR ≥ 70% | ||||
| Age, mean (SD) years | 48.69(8.94) | 47.65(10.59) | 48.10(9.91) | 0.11 | 0.06 | 58.72(7.19) | 58.04(7.99) | 57.44(7.31) | 0.09 | 0.18 |
| Sex (% women) | 59.57 | 66.25 | 67.56 | −0.14 | −0.17 | 26.39 | 25.08 | 24.45 | 0.03 | 0.04 |
| High‐risk alcohol intake (%) | 2.65 | 2.01 | 1.53 | 0.04 | 0.08 | 6.63 | 4.96 | 4.71 | 0.07 | 0.08 |
| Smokers (%) | 30.83 | 29.34 | 26.22 | 0.03 | 0.1 | 48.56 | 54.03 | 56.99 | −0.11 | −0.17 |
| Diabetes (%) | 1.53 | 1.19 | 1.28 | 0.03 | 0.02 | 11.13 | 9.8 | 8.71 | 0.04 | 0.08 |
| Hypertension (%) | 11.32 | 8.5 | 9.79 | 0.09 | 0.05 | 33.47 | 31.19 | 29.32 | 0.05 | 0.09 |
| Dyslipidemia (%) | 2.34 | 1.3 | 1.31 | 0.08 | 0.08 | 15.17 | 13.01 | 10.86 | 0.06 | 0.13 |
| Obesity (%) | 29.91 | 28.88 | 28.79 | 0.02 | 0.02 | 43.81 | 42.81 | 42.22 | 0.02 | 0.03 |
| Chronic kidney disease (%) | 0.16 | 0.14 | 0.14 | 0.01 | 0.01 | 0.52 | 0.42 | 0.38 | 0.01 | 0.02 |
| Blood pressure | ||||||||||
| Systolic, mean (SD), mm Hg | 125.28(14.83) | 124.30(14.64) | 124.65(14.70) | 0.07 | 0.04 | 138.04(15.62) | 138.55(15.77) | 139.02(16.21) | −0.03 | −0.06 |
| Diastolic, mean (SD), mm Hg | 76.66(9.36) | 76.26(9.09) | 76.35(9.00) | 0.04 | 0.03 | 81.78(9.98) | 82.12(9.80) | 82.39(9.74) | −0.04 | −0.06 |
| Total cholesterol, mean (SD), mmol/L | 5.22(0.60) | 5.25(0.75) | 5.26(0.73) | −0.04 | −0.05 | 5.71(0.67) | 5.77(0.83) | 5.81(0.80) | −0.08 | −0.14 |
| Total cholesterol, mean (SD), mg/dl | 202.02(23.10) | 203.10(29.01) | 203.28(28.21) | −0.04 | −0.04 | 220.88(25.97) | 223.27(32.13) | 224.80(31.08) | −0.08 | −0.13 |
| LDL cholesterol, mean (SD), mmol/L | 3.28(0.60) | 3.35(0.71) | 3.33(0.69) | −0.09 | −0.07 | 3.54(0.63) | 3.60(0.75) | 3.62(0.74) | −0.09 | −0.11 |
| LDL cholesterol, mean (SD), mg/dl | 126.99(23.29) | 129.40(27.60) | 128.81(26.75) | −0.09 | −0.07 | 136.96(24.39) | 139.40(29.01) | 139.86(28.45) | −0.09 | −0.10 |
| HDL cholesterol, mean (SD), mmol/L | 1.52(0.39) | 1.54(0.38) | 1.55(0.37) | −0.04 | −0.06 | 1.26(0.30) | 1.26(0.30) | 1.26(0.29) | 0.01 | 0.02 |
| HDL cholesterol, mean (SD), mg/dl | 58.93(15.21) | 59.53(14.53) | 59.77(14.19) | −0.04 | −0.05 | 48.86(11.55) | 48.78(11.51) | 48.59(11.05) | 0.01 | 0.02 |
| Serum triglycerides, mmol/L | 1.21(0.67) | 1.40(1.05) | 1.39(1.09) | −0.21 | −0.2 | 1.53(0.90) | 1.84(1.44) | 1.78(1.19) | −0.26 | −0.23 |
| Serum triglycerides, mg/dl | 107.14(59.74) | 123.91(93.29) | 123.14(96.31) | −0.21 | −0.19 | 135.33(79.58) | 162.53(127.96) | 157.22(105.57) | −0.26 | −0.23 |
| Glucose, mmol/L | 5.09(0.93) | 5.06 (1.39) | 5.13 (1.6) | 0.02 | −0.03 | 5.8(1.52) | 5.79(2.12) | 5.8(2.21) | 0.00 | 0.00 |
| Glucose, mg/dl | 91.59(16.67) | 91.11(25.00) | 92.35(28.73) | 0.02 | −0.03 | 104.45(27.35) | 104.29(38.07) | 104.35(39.8) | 0.00 | 0.00 |
| Body mass index, kg/m2 | 27.29(5.22) | 27.29(5.36) | 27.3(5.28) | 0.00 | 0.00 | 29.33(5.27) | 29.2(5.31) | 29.13(5.17) | 0.02 | 0.04 |
| 10‐year CHD risk, mean (SD) | 1.99(1.10) | 1.86(1.15) | 1.86(1.11) | 0.12 | 0.12 | 6.04(0.70) | 6.03(0.70) | 6.07(0.73) | 0.02 | −0.04 |
| ≥7.5‐9.9% | SDiffb | SDiffb | ≥10‐19.9% | SDiffa | SDiffa | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variables | Statin nonusers | Statin users MPR<70% | Statin users MPR≥70% | Statin nonusers | Statin users MPR<70% | Statin users MPR≥70% | ||||
| Age, mean (SD) years | 61.74(6.85) | 61.34(7.11) | 61.02(7.14) | 0.06 | 0.1 | 64.85(5.82) | 64.32(6.24) | 63.93(6.41) | 0.09 | 0.15 |
| Sex (% women) | 16.23 | 16.49 | 17.19 | −0.01 | −0.03 | 9.46 | 9.63 | 9.99 | −0.01 | −0.02 |
| High‐risk alcohol intake (%) | 8.13 | 6.83 | 6.66 | 0.05 | 0.06 | 8.66 | 9.81 | 6.52 | −0.04 | 0.08 |
| Smokers (%) | 60.42 | 64.44 | 66.88 | −0.08 | −0.13 | 72.17 | 73.9 | 74.23 | −0.04 | −0.05 |
| Diabetes (%) | 21.53 | 19.82 | 19.32 | 0.04 | 0.06 | 33.34 | 31.71 | 31.09 | 0.03 | 0.05 |
| Hypertension (%) | 40.75 | 37.91 | 36.12 | 0.06 | 0.1 | 49.12 | 45.93 | 43.68 | 0.06 | 0.11 |
| Dyslipidemia (%) | 19.28 | 17.93 | 15.54 | 0.03 | 0.1 | 25.94 | 23.79 | 22.09 | 0.05 | 0.09 |
| Obesity (%) | 45.34 | 44.58 | 44.29 | 0.02 | 0.02 | 47.45 | 47.52 | 46.41 | 0 | 0.02 |
| Chronic kidney disease (%) | 0.89 | 0.85 | 0.76 | 0 | 0.02 | 1.23 | 1.18 | 1.15 | 0 | 0.01 |
| Blood pressure | ||||||||||
| Systolic, mean (SD), mm Hg | 140.79(15.81) | 141.24(16.38) | 141.41(16.56) | −0.03 | −0.04 | 144.60(15.72) | 144.81(16.25) | 144.93(16.23) | −0.01 | −0.02 |
| Diastolic, mean (SD), mm Hg | 82.24(10.19) | 82.42(10.14) | 82.41(9.79) | −0.02 | −0.02 | 82.52(10.00) | 82.92(10.13) | 83.10(10.13) | −0.04 | −0.06 |
| Total cholesterol, mean (SD), mmol/L | 5.77(0.72) | 5.86(0.81) | 5.88(0.83) | −0.11 | −0.14 | 5.88(0.77) | 5.97(0.77) | 6.01(0.86) | −0.12 | −0.17 |
| Total cholesterol, mean (SD), mg/dl | 223.16(27.94) | 226.48(31.47) | 227.25(32.23) | −0.11 | −0.13 | 227.21(29.76) | 230.68(29.66) | 232.42(33.07) | −0.12 | −0.16 |
| LDL cholesterol, mean (SD), mmol/L | 3.56(0.61) | 3.66(0.70) | 3.66(0.69) | −0.14 | −0.15 | 3.61(0.63) | 3.70(0.69) | 3.71(0.69) | −0.13 | −0.15 |
| LDL cholesterol, mean (SD), mg/dl | 137.83(23.54) | 141.38(27.10) | 141.55(26.86) | −0.14 | −0.14 | 139.72(24.21) | 142.92(26.50) | 143.50(26.72) | −0.13 | −0.14 |
| HDL cholesterol, mean (SD), mmol/L | 1.22(0.29) | 1.22(0.28) | 1.22(0.26) | −0.01 | −0.02 | 1.15(0.26) | 1.16(0.26) | 1.16(0.25) | 0 | 0 |
| HDL cholesterol, mean (SD), mg/dl | 47.17(11.21) | 47.26(10.82) | 47.34(10.03) | −0.01 | −0.01 | 44.66(9.95) | 44.69(10.04) | 44.71(9.51) | −0.00 | −0.00 |
| Serum triglycerides,mean (SD), mmol/L | 1.61(0.95) | 1.90(1.34) | 1.91(1.48) | −0.26 | −0.25 | 1.71(1.05) | 2.04(1.58) | 2.00(1.61) | −0.25 | −0.22 |
| Serum triglycerides,mean (SD), mg/dl | 142.18(84.47) | 168.52(118.53) | 169.61(131.15) | −0.26 | −0.24 | 151.03(92.73) | 180.93(140.15) | 177.12(142.49) | −0.25 | −0.21 |
| Glucose, mmol/L | 6.19(1.85) | 6.19(2.32) | 6.22(2.60) | 0.00 | −0.02 | 6.682.08 | 6.662.42 | 6.72.89 | 0.01 | −0.01 |
| Glucose, mg/dl | 111.4(33.31) | 111.43(41.75) | 112.01(46.86) | 0.00 | −0.02 | 120.1637.42 | 119.9143.63 | 120.5352.09 | 0.01 | −0.01 |
| Body Mass Index, Kg/m2 | 29.52(5.21) | 29.41(5.10) | 29.42(5.00) | 0.02 | 0.02 | 29.75.12 | 29.694.9 | 29.614.79 | 0.00 | 0.02 |
| 10‐year CHD risk, mean (SD) | 8.59(0.70) | 8.59(0.71) | 8.61(0.71) | −0.01 | −0.03 | 12.98(2.35) | 13.00(2.44) | 12.89(2.56) | −0.01 | 0.03 |
a
SDiff: standardized differences respect to nonusers.
SDiff: standardized differences respect to nonusers.