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. 2018 May 4;28(5):496–505. doi: 10.1111/jon.12519

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© 2018 The Authors. Journal of Neuroimaging published by Wiley Periodicals, Inc. on behalf of American Society of Neuroimaging

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Box and whisker plots of distribution volume (V_T) values (left panel) and influx rate (K ₁) values (right panel) estimated using two tissue compartment model and partial volume corrected image‐derived input function showing the difference between healthy volunteers (HVs) and patients with Parkinson's disease (PD) indicating no significant difference in influx, but a significant difference in V_T values. (left, n = 19 HV and n = 18 PD, P = .0031; right, n = 19 HV and n = 18 PD, P = .60).