Table 1.
Comparison of Both Methods Including 44 Healthy Control Subjects
| Region | FS6 | CAT12 | Δ (%) mean | Cohens' d | R 2 |
|---|---|---|---|---|---|
| Banks superior temporal sulcus | 2.32 ± .11 | 2.66 ± .12 | 13.4 | 2.86 | .62 |
| Caudal anterior‐cingulate cortex (n.s.) | 2.52 ± .26 | 2.55 ± .28 | 6.4 | .11 | .43 |
| Caudal middle frontal gyrus | 2.44 ± .11 | 2.77 ± .12 | 12.5 | 2.76 | .76 |
| Cuneus cortex | 1.87 ± .09 | 2.05 ± .10 | 9.1 | 1.97 | .54 |
| Entorhinal cortex | 3.20 ± .32 | 3.95 ± .44 | 20.8 | 1.97 | .34 |
| Fusiform gyrus | 2.50 ± .11 | 2.73 ± .17 | 9.0 | 1.65 | .20 |
| Inferior parietal cortex | 2.30 ± .12 | 2.68 ± .12 | 15.3 | 3.09 | .77 |
| Inferior temporal gyrus | 2.64 ± .14 | 3.05 ± .17 | 14.4 | 2.66 | .49 |
| Isthmus‐cingulate cortex | 2.24 ± .13 | 2.51 ± .19 | 12.0 | 1.72 | .18 |
| Lateral occipital cortex | 2.12 ± .09 | 2.43 ± .11 | 13.7 | 3.11 | .23 |
| Lateral orbital frontal cortex | 2.55 ± .11 | 3.06 ± .13 | 18.0 | 4.06 | .20 |
| Lingual gyrus | 1.99 ± .09 | 2.12 ± .10 | 6.7 | 1.44 | .36 |
| Medial orbital frontal cortex | 2.36 ± .12 | 2.78 ± .13 | 16.5 | 3.47 | .16 |
| Middle temporal gyrus | 2.65 ± .10 | 3.10 ± .15 | 15.7 | 3.54 | .55 |
| Parahippocampal gyrus | 2.53 ± .25 | 2.73 ± .21 | 8.8 | .85 | .46 |
| Paracentral lobule | 2.28 ± .15 | 2.34 ± .15 | 4.2 | .39 | .57 |
| Pars opercularis | 2.42 ± .10 | 2.80 ± .12 | 14.6 | 3.36 | .67 |
| Pars orbitalis | 2.56 ± .16 | 2.93 ± .14 | 13.8 | 2.49 | .48 |
| Pars triangularis | 2.30 ± .12 | 2.72 ± .13 | 17.1 | 3.39 | .71 |
| Pericalcarine cortex | 1.61 ± .09 | 1.84 ± .13 | 13.6 | 2.06 | .40 |
| Postcentral gyrus | 1.94 ± .09 | 2.20 ± .12 | 12.5 | 2.41 | .72 |
| Posterior‐cingulate cortex | 2.33 ± .15 | 2.44 ± .14 | 6.3 | .76 | .24 |
| Precentral gyrus (n.s.) | 2.44 ± .12 | 2.43 ± .14 | 3.1 | –.12 | .53 |
| Precuneus cortex | 2.22 ± .11 | 2.54 ± .12 | 13.4 | 2.85 | .75 |
| Rostral anterior cingulate cortex | 2.75 ± .21 | 3.11 ± .22 | 12.4 | 1.70 | .34 |
| Rostral middle frontal gyrus | 2.25 ± .10 | 2.69 ± .12 | 17.8 | 3.88 | .76 |
| Superior frontal gyrus | 2.54 ± .11 | 2.90 ± .12 | 13.0 | 2.99 | .84 |
| Superior parietal cortex | 2.07 ± .13 | 2.37 ± .12 | 13.4 | 2.40 | .78 |
| Superior temporal gyrus | 2.53 ± .12 | 2.79 ± .14 | 9.9 | 2.00 | .85 |
| Supramarginal gyrus | 2.38 ± .10 | 2.71 ± .12 | 13.2 | 3.09 | .82 |
| Frontal pole | 2.63 ± .20 | 2.95 ± .19 | 12.0 | 1.66 | .56 |
| Temporal pole | 3.36 ± .28 | 4.01 ± .35 | 17.7 | 2.07 | .63 |
| Transverse temporal cortex | 2.24 ± .18 | 2.34 ± .16 | 6.2 | .58 | .47 |
| Insula | 2.83 ± .14 | 3.62 ± .22 | 24.3 | 4.35 | .53 |
Mean cortical thickness values, standard deviations, and statistics for each region processed with FreeSurfer (FS6) and CAT12. 32 out of 34 regions showed significant higher estimates for CAT12.
Legend: n.s. = not significant; Δ (%) mean = mean percentage difference between both methods; R 2 = coefficient of determination.