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Molecular response in patients with CML: BCR‐ABL1 transcript levels according to the International Scale (Baccarani et al, 2014; Cross et al, 2015)
| BCR‐ABL IS, % | Log reduction from standardised baseline | MR category | Minimum number of ABL1 transcripts |
|---|---|---|---|
| 100 | 0 | – | – |
| ≤0·1 | 3 | MR3 (MMR) | >10 000 |
| ≤0·01 | 4 | MR4 | 10 000–31 999 |
| ≤0·0032 | 4·5 | MR4·5 | 32 000–99 999 |
| ≤0·001 | 5 | MR5 | ≥100 000 |
CML, chronic myeloid leukaemia; MMR, major molecular response; MR, molecular response.
