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. 2018 Apr 16;18(9):2274–2284. doi: 10.1111/ajt.14709

Figure 3.

Figure 3

Impact of donor‐specific HLA antibodies (DSAs) on graft survival for deceased‐donor transplants. A. Adjusted Kaplan–Meier estimates (AKME) for 1‐year death‐censored graft survival according to the presence of pretransplant DSAs for living‐donor transplants only (n = 1487). B. AKME for 1‐year death‐censored graft survival according to the presence of pretransplant DSAs for deceased‐donor transplants only (n = 3237). C. Analysis of long‐term effect of pretransplant DSAs starting at 1 year after transplant for living‐donor transplants only (n = 1417). D. Analysis of long‐term effect of pretransplant DSAs starting at 1 year after transplant for deceased‐donor transplants only (n = 2834). E. AKME for death‐censored graft survival according to the presence of pretransplant HLA class I (A/B) and/or II (DR/DQ) DSAs for living‐donor transplants only (n = 1487). F. AKME for death‐censored graft survival according to the presence of pretransplant HLA class I (A/B) and/or II (DR/DQ) DSAs for deceased‐donor transplants only (n = 3237). All AKME were adjusted for the same covariates: recipient age (quadratic) and donor age (quadratic), donor type (living or deceased; for the total cohort only), cold ischemia time (for donation after brain death [DBD] and donation after cardiac death [DCD]), time on dialysis in years (quadratic) and induction therapy with interleukin‐2 receptor blocker [Color figure can be viewed at http://www.wileyonlinelibrary.com]