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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Jul 17;121:180–189. doi: 10.1016/j.yjmcc.2018.07.243

Table 1. Transgenic overexpressing mice clustering.

Groups identified by k-means clustering of mouse models by similarity of global network responses to transgenic overexpression of a single network species.

Group Transgenic mouse models
TG1 αAR, IGF1R, AT1R, ERBB, Gαq/11
TG2 βAR, Gsα
TG3 AC, PKA
TG4 IL6/IL6R, gp130LIFR, Integrins, PKC, Ras
TG5 GSK3β
TG6 MEK12, MEK7, MEK5, RhoA, SRF, GATA4, MEF2, NFAT, STAT, Calmodulin, calcineurin, CaMK
TG7 Rac1, MEK36, TAK1,
TG8 TNFα, PI3K, Akt