Table 2.

Changes in MDS‐UPDRS Parts 1 to 4 and metabolic parameters.

	Low‐fat group (n = 23)			Ketogenic group (n = 24)
	Baseline	Week 8	Change	Baseline	Week 8	Change	P Value (between groups)
Part 1 (nonmotor daily living experiences)	8.96  ± 4.34	7.96  ± 6.56	−0.99 ± 3.63	11.15  ± 4.15	6.57  ± 4.09	−4.58 ± 2.17	<0.001
Part 2 (motor daily living experiences)	11.13  ± 5.59	9.80  ± 6.81	−1.33 ± 3.28	12.75  ± 5.30	9.62  ± 5.64	−3.13 ± 4.01	0.11
Part 3 (motor examination)	34.93  ± 13.40	26.36  ± 13.58	−8.58 ± 5.50	36.48  ± 13.29	30.20  ± 12.88	−6.27 ± 4.07	0.055
Part 4 (motor complications)	4.33  ± 4.44	3.54  ± 4.86	−0.79 ± 2.71	4.90  ± 3.95	3.33  ± 3.02	−1.56 ± 2.45	0.32
Weight (kg)	78.13  ± 19.45	73.26  ± 17.99	−4.87 ± 2.47	83.71  ± 19.38	79.34  ± 17.13	−4.37 ± 3.00	0.55
BMI	26.96  ± 6.35	25.28  ± 5.95	−1.67 ± 0.79	27.77  ± 5.29	26.31  ± 4.46	−1.46 ± 1.01	0.30
HbA1C (mmol/mol)	34.67 ± 5.22	34.18 ± 3.74	−0.49 ± 2.72	36.15 ± 8.60	34.72 ± 5.68	−1.42 ± 4.12	0.095
Triglycerides (mmol/L)	1.71  ± 0.88	1.45  ± 0.55	−0.26 ± 0.74	1.81  ± 1.18	1.71  ± 0.81	−0.10 ± 0.63	0.46
HDL (mmol/L)	1.51  ± 0.47	1.40  ± 0.38	−0.11 ± 0.22	1.50  ± 0.44	1.89  ± 0.75	+0.40 ± 0.59	<0.001
LDL (mmol/L)	2.74  ± 0.82	2.35  ± 0.77	−0.40 ± 0.30	2.73  ± 1.06	3.42  ± 1.37	+0.70 ± 0.67	<0.001
Total cholesterol (mmol/L)	5.03  ± 1.00	4.40  ± 0.93	−0.63 ± 0.51	5.03  ± 1.05	5.98  ± 1.39	+0.94 ± 0.80	<0.001
Urate (mmol/L)	0.30  ± 0.08	0.28  ± 0.08	−0.02 ± 0.03	0.30  ± 0.08	0.33  ± 0.08	+0.03 ± 0.05	<0.001
CRP (mmol/L)	2.95  ± 2.99	1.95  ± 1.79	−1.00 ± 3.57	1.95  ± 1.59	2.24  ± 1.26	+0.29 ± 1.93	0.10

Values are presented as mean ± standard deviation.

Bolded values highlight changes in scores and parameters; due to round‐off, some change values differ by 0.01 from the absolute value differences.

P values refer to changes in scores and parameters between (not within) groups.