Table 2.

Multinomial Logistic Regression Analysis of Variables Associated With Subtypes of Gastroesophageal Reflux Disease

	Control	ERD		NERD		AEE
		OR (95% CI)	P-value	OR (95% CI)	P-value	OR (95% CI)	P-value
Age	1.00	1.01 (0.99–1.02)	0.495	1.00 (0.99–1.00)	0.157	1.00 (1.00–1.01)	0.524
Sex (female)	1.00	0.68 (0.39–1.18)	0.168	1.42 (1.20–1.69)	< 0.001	0.38 (0.31–0.48)	< 0.001
BMI	1.00	1.18 (1.13–1.24)	< 0.001	1.04 (1.02–1.06)	< 0.001	1.12 (1.09–1.14)	< 0.001
Current smoking	1.00	2.28 (1.47–3.55)	< 0.001	1.37 (1.18–1.59)	< 0.001	1.46 (1.26–1.70)	< 0.001
Alcohol use	1.00	1.44 (0.88–2.34)	0.144	0.96 (0.83–1.10)	0.531	1.25 (1.05–1.49)	0.012
Marriage status	1.00	0.45 (0.27–0.74)	0.002	0.71 (0.58–0.87)	< 0.001	0.96 (0.76–1.22)	0.728
Diabetes mellitus	1.00	0.51 (0.22–1.18)	0.116	0.65 (0.48–0.87)	0.004	1.13 (0.91–1.41)	0.269
Aspirin use	1.00	0.80 (0.43–1.49)	0.480	1.00 (0.80–1.25)	0.993	1.11 (0.91–1.36)	0.310
NSAID use	1.00	0.59 (0.25–1.40)	0.230	1.19 (0.92–1.53)	0.180	0.93 (0.73–1.19)	0.567
Helicobacter pylori seropositivity	1.00	0.32 (0.23–0.46)	< 0.001	0.96 (0.86–1.08)	0.540	0.36 (0.31–0.40)	< 0.001
Atrophic gastritis	1.00	0.55 (0.35–0.87)	0.010	0.88 (0.76–1.02)	0.084	0.80 (0.69–0.93)	0.003
Intestinal metaplasia	1.00	1.10 (0.58–2.11)	0.763	0.79 (0.64–0.99)	0.038	0.84 (0.67–1.06)	0.147
State anxiety	1.00	2.20 (1.27–3.81)	0.005	1.89 (1.53–2.33)	< 0.001	1.25 (0.96–1.65)	0.103
Trait anxiety	1.00	1.07 (0.44–2.59)	0.882	1.78 (1.34–2.35)	< 0.001	1.27 (0.83–1.96)	0.270
Depression	1.00	2.23 (1.18–4.22)	0.013	2.21 (1.75–2.80)	< 0.001	1.29 (0.93–1.80)	0.132

ERD, erosive reflux disease; NERD, non-erosive reflux disease; AEE, asymptomatic erosive esophagitis; BMI, body mass index.