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. 2018 Oct 1;24(4):669–675. doi: 10.5056/jnm18049

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© 2018 The Korean Society of Neurogastroenterology and Motility

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of different doses of trimebutine on the lower gastrointestinal (GI) transit. (A) The effect of different doses of trimebutine on the number of cumulative fecal pellet output (FPO) in OS model of guinea pigs. (B) The effect of different doses of trimebutine on the cumulative fecal weight (g) in OS model of guinea pigs. Data represents mean ± SEM (n = 6/group). *P < 0.05, **P < 0.01 in comparison to corticotropin-releasing factor (CRF) 10 μg/kg only.