Table 6.
Comparison of Tissue Eosinophil Counts Among the Subtypes of Functional Abdominal Pain Disorders
| Anatomical region | IBS (n = 37) | Overlap (n = 9) | Non-IBS (n = 10) | P-valuea |
|---|---|---|---|---|
| Gastric antrum | 3.6 ± 6.6 | 5.4 ± 6.4 | 4.7 ± 3.6 | 0.249 |
| Gastric body | 2.1 ± 2.2 | 3.9 ± 3.8 | 3.3 ± 2.3 | 0.204 |
| Duodenum | 12.8 ± 8.5 | 21.4 ± 22.8 | 12.9 ± 3.9 | 0.716 |
| Terminal ileum | 24.1 ± 19.4 | 23.0 ± 8.0 | 7.5 ± 3.5 | 0.242 |
| Cecum | 22.5 ± 20.7 | 24.4 ± 20.7 | 24.0 ± 13.3 | 0.800 |
| Ascending colon | 17.2 ± 10.3 | 13.0 ± 6.4 | 11.7 ± 8.2 | 0.518 |
| Transverse colon | 14.0 ± 10.3 | 12.7 ± 7.5 | 9.3 ± 2.4 | 0.853 |
| Descending colon | 13.3 ± 8.5 | 9.0 ± 3.8 | 14.2 ± 12.9 | 0.411 |
| Sigmoid colon | 12.8 ± 15.2 | 10.1 ± 7.5 | 10.5 ± 6.9 | 0.916 |
| Rectum | 3.3 ± 3.1 | 3.7 ± 2.5 | 2.8 ± 3.2 | 0.606 |
a
P-value between normal control and with functional abdominal pain disorders (FAPDs) was calculated by Kruskal-Wallis test.
IBS, irritable bowel syndrome; FD, functional dyspepsia; FAP-NOS, functional abdominal pain not otherwise specified; AM, abdominal migraine.
Total of 56 children with FAPDs were classified as IBS (n = 37), IBS + FD (n = 5), IBS + FAP-NOS (n = 3), IBS + AM (n = 1), FAP-NOS (n = 6), FD (n = 3), and AM (n = 1).
Overlap group included IBS + FD (n = 5), IBS + FAP-NOS (n = 3), and IBS + AM (n = 1).
Non-IBS group included FAP-NOS (n = 6), FD (n = 3), and AM (n = 1).