Table 1:

C-CHANGE guideline partners and methodology

Guideline group	Grading system or methodology
Canadian Action Network for the Advancement, Dissemination and Adoption of Practice-Informed Tobacco Treatment1	This independent expert body in guideline review conducted a review and identified 6 guidelines that met criteria for quality and applicability to local context. Summary statements were extracted and assigned a grade of recommendation and level of evidence by a second expert panel.2 The ADAPTE framework was used to guide the contextual adaptation (www.g-i-n.net/working-groups/adaptation/history); AGREE II was used to rate and select appropriate guidelines.
Canadian Cardiovascular Society – guideline for the management of heart failure3	GRADE
Canadian Cardiovascular Society – guideline for the management of dyslipidemia4	GRADE
Canadian Association of Cardiovascular Prevention and Rehabilitation	Hypertension Canada process (www.hypertension.ca)
Canadian Society for Exercise Physiology5	The Canadian Society for Exercise Physiology guideline steering committee used the AMSTAR tool (www.amstar.ca/docs/AMSTARguideline.pdf) to assess the methodological quality of the systematic reviews; conclusions from the reviews were assigned a level of evidence6–9 based on quality of the study, and level of evidence was used to develop appropriate wording for the guideline.
Diabetes Canada10	Diabetes Canada process (www.guidelines.diabetes.ca/)
Hypertension Canada11	Hypertension Canada process (www.hypertension.ca)
Canadian Association of Bariatric Physicians and Surgeons/Obesity Canada12	GRADE
Heart and Stroke Foundation13	GRADE

Note: AGREE II = Appraisal of Guidelines for Research & Evaluation II, AMSTAR = Assessment of Multiple Systematic Reviews, C-CHANGE = Canadian Cardiovascular Harmonized National Guidelines Endeavour, GRADE = the Grading of Recommendations, Assessment, Development and Evaluation framework.¹⁴