Patients with mild to severe form of MPS IVA. A. Images of patients with distinct differences in clinical features from mild form, immediate form, and severe form of MPS IVA (adapted from Educational CD for Morquio and permitted by Carol Ann Foundation). B. Images of a patient with severe form of MPS IVA. From left to right: patient age is 7, 8, 11, 16, and 16 years (adapted from Educational CD for Morquio and permitted by Carol Ann Foundation) [33].