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GCH1 block 1 (14kb) haplotype analysis with CPI and utilization groups
| Haplotype | Frequency (%) | 0 vs 1 or More Utilizations |
0–3 vs 4 or More Utilizations |
CPI |
|||
|---|---|---|---|---|---|---|---|
| OR | p-value | OR | p-value | Estimate | p-value | ||
| CCT | 18 | 1.01 | 0.989 | 1.09 | 0.819 | 4.02 | 0.066 |
| CTC | 19 | 1.75 | 0.321 | 2.04 | 0.050 | 2.33 | 0.282 |
SNP order in haplotype (rs10483639[G>C]– rs752688[C>T]–rs4411417[T>C]). Reference haplotype was GCT (frequency = 61%). Regression models are adjusted for covariates (age, sex, and sickle cell type).
