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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Exp Hematol. 2018 Jul 19;66:42–49. doi: 10.1016/j.exphem.2018.07.004

Table 8.

GCH1 block 2 (18kb) haplotype analysis with CPI and utilization groups

Haplotype Frequency (%) 0 vs 1 or More Utilizations
 0– 3 vs 4 or More Utilizations
 CPI
OR p-value OR p-value Estimate p-value
TC 35 0.80 0.637 0.31 0.001 −3.61 0.060
TT 28 0.64 0.367 0.54 0.089 0.30 0.886

SNP order in haplotype (rs3783641[T>A]– rs8007267[T>C]). Reference haplotype was AT (frequency = 37%). Regression models are adjusted for covariates (age, sex, and sickle cell type).