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. 2018 Oct 7;24(37):4263–4271. doi: 10.3748/wjg.v24.i37.4263

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©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Pancreatic-duodenal homeobox-1 overexpression regulated the expression of heat shock proteins in gastric cancer SGC7901 cells. A: Immunoblotting analysis confirmed the enhanced expression of PDX1 protein after PDX1-pcDNA transfection in SGC7901 cells. It also revealed that PDX1 overexpression could downregulate the expression of HSP27, HSP60, and HSP70 proteins in SGC-PDX1 cells; B: Quantitative analysis of the results of immunoblotting indicated that HSP70 protein was significantly decreased in SGC-PDX1 cells. ^aP < 0.05.