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. 2018 Oct 8;8:14975. doi: 10.1038/s41598-018-33207-2

Figure 6.

Figure 6

Craniofacial skeletal preparations from control and NCCDlx5 E18.5 foetuses. (A,A’) Lateral views of the head of control (A) and NCCDlx5 (A’) E18.5 foetuses. In NCCDlx5 mice the maxilla is deformed with thickening of the zygomatic process while the jugal and the premaxillary bones are shortened. (B,B’) Dentary bones of control (B) and NCCDlx5 (B’) E18.5 foetuses. The coronoid process (cp) is hypoplastic in NCCDlx5 mice while the Meckelian cartilage (Mc) and the malleus (m) are well-formed. (C,C’) Jaw joint region of control (C) and NCCDlx5 (C’) E18.5 mouse foetuses. The zygomatic and retroarticular processes (ra) of the squamosal (sq) are missing and the coronoid process of the dentary bone is hypoplastic in NCCDlx5 mice. (D,D’) Middle ear components of control (D) and NCCDlx5 (D’) E18.5 mouse foetuses. The incus (i) is deformed and dislocated from the stapes (st) fused to the styloid process (sp) in NCCDlx5 mice. Abbreviations: cp, coronoid process; dt, dentary bone; i, incus; jb, jugal bone; m, malleus; Mc, Meckel’s cartilage; pmx, premaxilla; ra, retroarticular process of squamosal; sp, styloid process; sq, squamosal; st, stapes; tr, ectotympanic ring; zp, zygomatic process of maxilla; zps, zygomatic process of squamosal.