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. 2018 Oct 8;8:14975. doi: 10.1038/s41598-018-33207-2

Figure 7.

Figure 7

Cranial base deformity in NCCDlx5 mice. Ventral (A,A’,C,C’) and dorsal (B, B’) views of the cranial base of E18.5 control (AC) and NCCDlx5 (A’,B’,C’) E18.5 mouse foetuses. In NCCDlx5 mice, palatal processes of the maxilla (white arrowhead in C,C’) and palatine (yellow arrowhead in C,C’) are defective. The paranasal cartilage (pnc), basisphenoid (bs) and the prechordal plate (pcp) are enlarged in width. Ectopic cartilaginous and osseous struts extended from the basisphenoid laterally and anteriorly, respectively (ect). Abbreviations: als, alisphenoidal bone; bo, basioccipital bone; bs, basisphenoidal bone; ect, ectopic structure; pcp, parachordal plate; px, premaxilla; pnc, paranasal cartilage; ptg, pterygoid.