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. 2018 Oct 8;8:14916. doi: 10.1038/s41598-018-33092-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Microbiota diversity indices of the different groups: (a) the bacterial richness of microbiota communities estimated by the Chao1 value. (b) The bacterial diversity of the microbiota communities estimated by Shannon index; (c) PCoA plot of unweighted UniFrac distance values and (d) weighted UniFrac distance values. All groups of α diversity indices (Chao1 and Shannon) were analyzed by two-way analysis of variance (ANOVA) followed Fisher’s LSD post hoc tests. *Indicates significant difference with P < 0.05, **Indicates P < 0.01 and ***Indicates P < 0.001; NS indicates lack of statistically significant difference.