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. 2018 Oct 8;8:14904. doi: 10.1038/s41598-018-33298-x

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Localization of predicted epitopes in the Atr-I model. A cartoon view of the structural model of the protein Atr-I is displayed. The residues that belong to the computational prediction are shown in pink (A) while the experimental epitopes and the cross-reactive regions between the different serum samples tested are indicated in blue (anti-Atr1) and orange respectively (anti-Bap1 and anti-Leuc-a) (B,C). The overlap of these methods is presented in (D) where the black regions correspond to the matching computational and experimental predictions.