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. 2018 Oct 8;7(10):80. doi: 10.1038/s41389-018-0091-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a NIH3T3 cells stably expressing pcDNA3, Vav1, oncVav1, E59K, D517E, and L801P were injected subcutaneously into athymic female NOD/SCID mice. The histogram shows the mean tumor sizes of 3 experiments 30 days following injection ( ± SE). Six mice were used for each group in each experiment. Differences between tumors generated by oncVav1, E59K, D517E, and Vav1 are, as indicated, highly significant (*unpaired Student’s t test). b Photographs of representative tumors 30 days post-injection are depicted