Table 3.
Genetic association of surfactant protein genes SFTPA1, SFTPB, and SFTPC with CF.
| Gene | SNP #1 ID | SNP #2 ID | Interaction type | x2 | p-value | |
|---|---|---|---|---|---|---|
| Genetic association of STFPB and SFTPC with CF by a single SNP | ||||||
| 1 | SFTPB | rs7316 | d | 6.9689 | 0.0083 | |
| 2 | SFTPC | rs1124 | d | 5.8674 | 0.0154 | |
| Genetic association of SFTPB and SFTPA1 with CF by intragenic SNP interaction | ||||||
| 3 | SFTPB | rs2077079 | rs3024798 | d1 | 3.2688 | 0.0325 |
| 4 | SFTPA1 | rs1136451 | rs1059057 | d2 | 2.7329 | 0.0469 |
| 5 | SFTPA1 | rs1136451 | rs4253527 | d2 | 3.5625 | 0.0238 |
Interaction type: d - dominant, in single SNPs.
Number 1 and 2 in interaction type column; represent SNP1 and SNP2.
The d1 stands for a dominant effect for SNP1, and d2 stands for a dominant effect for SNP2.