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. 2018 Oct 2;11:362. doi: 10.3389/fnmol.2018.00362

FIGURE 3.

FIGURE 3

Arhgef6 knockdown mice show progressive hearing loss. (A) The ABR thresholds of wildtype and Arhgef6 knockdown mice from P21 to P90 in response to click stimuli. (B) ABR threshold of wildtype and Arhgef6 knockdown mice at P30 in response to 4–32 kHz tone pips. (C) ABR thresholds of wildtype and Arhgef6 knockdown mice at P90 in response to 4–32 kHz tone pips. (D) The DPOAE thresholds of Arhgef6 knockdown mice and wildtype mice at P90 in response to 4–32 kHz tone pips. Data are presented as the mean ± SEM, n = 10/genotype. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.