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. 2018 Oct 2;9:2125. doi: 10.3389/fimmu.2018.02125

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Copyright © 2018 Garcia-Carmona, Ting, Radigan, Athuluri Divakar, Chavez, Meffre, Cerutti and Cunningham-Rundles.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) TACI isoforms are differentially expressed in B cell subpopulations. Surface and intracellular TACI isoforms frequency in freshly isolated peripheral blood CD19+ cells. Data shows the mean ± SEM of 4 independent experiments for 4 normal donors. *p < 0.05, two-tailed paired Student t-test. (B) Percent of expression of surface and intracellular (C) TACI isoforms in different B cell subpopulations isolated from blood of 4 donors: Naïve (IgD+CD27-), Transitional (Tr) (IgM+CD38+), Marginal Zone (MZ) (IgD+CD27+), Switched Memory (SwMe) (IgD-CD27+), and Plasmablasts (PB) (IgD-CD27^hiCD38^hi). Data compile the results for 4 experiments. Data shows the mean ± SEM. *p < 0.05, two-tailed paired Student t-test.