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CYP2D6 genotype and metabolizer category.
| Frequency, % (n) | Genotype | Activity | Category |
|---|---|---|---|
| PM | None | Two null alleles (CYP2D6 *4) | *4(AA): 3.6 (3) |
| IM | Reduced | One null allele (CYP2D6 *4, *10, *17) | *4(GA): 48.8 (41) |
| *10(CT): 26.2 (22) | |||
| *17(CT): 3.6 (3) | |||
| EM | Normal | Two wild-type/normal alleles | *3(AA): 100.0 (84) |
| (CYP2D6 *3, *4, *10, *17) | *4(GG): 47.6 (40) | ||
| *10(CC): 73.8 (62) | |||
| *17(CC): 96.4 (81) |
CYP2D6, cytochrome P450 2D6; PM, poor metabolizer; IM, intermediate metabolizer; EM, extensive metabolizer.
