Table 4.
Distribution of CTLA4 (-CT60) genotypes in Tunisian AIH patients and controls.
| CTLA4 (-CT60) Genotypes | AIH Patients (n = 50) |
Controls (n = 100) |
p | OR (95% CI) | ||
|---|---|---|---|---|---|---|
| n | GF (%) | n | GF (%) | |||
| A/A | 4 | 8 | 22 | 22 | 0.039 | 0.30 [0.1–0.95] |
| A/G | 29 | 58 | 50 | 50 | 0.38 | – |
| G/G | 17 | 34 | 28 | 28 | 0.57 | – |
| CTLA 4 (-CT60) Alleles | AIH Patients |
Controls |
p | OR (95% CI) | ||
| 2n | AF (%) | 2n | (95% CI) | |||
| G | 63 | 63 | 106 | 53 | 0.10 | - |
| A | 37 | 37 | 94 | 0.47 | 0.10 | |
n: number of subjects, AIH: Autoimmune Hepatitis, GF: Genotype frequency, OR: odds ratio, CI: Confidence interval. P value calculated by the Fisher exact probability test.