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. 2018 Sep 1;8(9):1847–1855.

Figure 3.

Figure 3

The RasGRP3 mutation can regulate the expression of NIS and TSHR and alter the iodine uptake ability in thyroid cancer cells. A. Expression of NIS and TSHR was detected in 8505C and BHT101 cells transfected with RasGRP3-MUT, RasGRP3-WT, or the empty vector in a western blot assay. B. The iodine uptake ability was measured in 8505C and BHT101 cells transfected with RasGRP3-MUT, RasGRP3-WT, or the empty vector. *P < 0.05 vs. vector group. **P < 0.01 vs. vector group. #P < 0.05 vs. RasGRP3 WT group. ##P < 0.01 vs. RasGRP3 WT group.