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. 2018 Sep 1;8(9):1801–1811.

Figure 6.

Figure 6

NBAT1-mediated suppression of autophgay inhibits NSCLC survival and chemoresistance. (A) The colony formation in control and NBAT1 knockdown A549 cells. (B) The cell viability in control and NBAT1 knockdown A549 cells was detected by CCK-8 assay. (C) The colony formation in control and NBAT1-overxpressing 95D cells. (D) The cell viability in control and NBAT1-overxpressing 95D cells was detected by CCK-8 assay. (E) The effects of ATG7 siRNA on the increase of cell viability induced by NBAT1 overexpression. (F) The effects of 3-MA on the increase of cell viability induced by NBAT1 overexpression. (G) Control and NBAT1 knockdown A549 cells were subjected to cisplatin for 24 or 48 h in the presence or absence of either 3-MA (10 mM) before performing CCK-8 assays. (H) Cells from (G) were analyzed for apoptosis. *P < 0.05; ns, no significance.