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2-DG deglycosylates PARPi-induced PD-L1 protein in TNBC. A. Western blot analysis of the PD-L1 protein expression of MDA-MB-231 cells treated with 2-DG and/or PARPi (talazoparib or olaparib). B. Western blot analysis of the PD-L1 protein expression of BT549 cells treated with 2-DG and/or PARPi (talazoparib or olaparib). C. PD-L1 expression and PD-1 binding on the surface of MDA-MB-231 cells treated with 2-DG and/or PARPi were analyzed with FACS. *P<0.05.
