Figure 6.

Inhibition of NF-κB suppresses the NF-κB signaling pathway and the effects of anti-miR-140-5p on the in vitro acute lung injury model. (A) NF-κB protein expression was determined by (B) western blot assays, as well as (C) TNF-α, (D) IL-1β, (E) IL-6 and (F) MPO levels. **P<0.01 vs. negative control group; ^##P<0.01 vs. anti-140-5p group. miR, microRNA; NF-κB, nuclear factor-κB; Anti-140-5p, downregulation of miR-140-5p group; NF-κB i, downregulation of miR-140-5p and NF-κB inhibitor group; TNF-α, tumor necrosis factor-α; IL, interleukin; MPO, myeloperoxidase.