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. 2018 Sep 7;16(5):4213–4224. doi: 10.3892/etm.2018.6710

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Figure 5. — miR-423 inhibits cisplatin-induced apoptosis in endometrial cancer cells. (A) The caspase 3/7 activity in HEC-1B cells transfected with miR-423 mimic following different doses of cisplatin treatment. (B) The caspase 3/7 activity in Ishikawa cells transfected with miR-423 following different doses of cisplatin treatment. (C) The apoptotic proteins levels in HEC-1B cells and Ishikawa cells following 4-µg/ml cisplatin treatment. The relative expression level of apoptotic proteins in (D) HEC-1B cells and (E) Ishikawa cells following transfection with miR-423 mimic by densitometric analysis. *P<0.05 vs. cisplatin or ctrl. miR, microRNA; ctrl, control; Bcl-2, B cell lymphoma-2; BAX, Bcl-2 associated X protein.