Figure 8.
miR-423 affected EMT protein expression and activated AKT expression in endometrial cancer cells. (A) The expression of EMT proteins in HEC-1B and Ishikawa cells following transfection with miR-423 mimic. The relative expression level of EMT proteins on (B) HEC-1B and (C) Ishikawa cells following transfection with miR-423 mimic, identified via densitometric analysis. (D) The expression of p-AKT, AKT and PTEN in HEC-1B and Ishikawa cells following transfection with miR-423 mimic. The relative expression level of proteins on (E) HEC-1B and (F) Ishikawa cells following transfection with miR-423 mimic, identified via densitometric analysis. *P<0.05 vs. ctrl. miR, microRNA; EMT, epithelial-mesenchymal transition; AKT, protein kinase B; p, phosphorylated; PTEN, phosphatase and tensin homolog; ctrl, control.