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. 2018 Sep 15;10(9):2848–2858.

Figure 4.

Figure 4

Correlations between differentially expressed exosomal miRNAs and clinical characteristics of OLP. (A) Differential expression of exosomal miRNAs in OLP patients and normal controls. All the results were analyzed by the 2-ΔΔCt method, and spike-in control cel-miR-39 was used as internal reference. Exosomal miR-34a-5p and miR-130b-3p were upregulated, whereas miR-301b-5p was significantly downregulated in OLP. However, no significant difference was found in the expression of exosomal miR-29c-3p or miR-144-3p. (B-D) The correlation between the expression level of circulating exosomal miRNAs and RAE scores: miR-34a-5p (B), miR-130b-3p (C), and miR-301b-3p (D). Significantly positive correlation was found between the expression of exosomal miR-34a-5p and RAE scores, indicating that exosomal miR-34a-5p was correlated to the severity of OLP. *P < 0.05; **P < 0.01.