Table 3.

Comparison of standard deviation of Tc-99m ECD brain perfusion SPECT study before (baseline) and after (at six-month) CD34+ cell therapy in 9 study patients

Variables	Median SD (Q1, Q3) (day 0)	Median SD (Q1, Q3) (6 M)	Median difference (Q1, Q3)	P*
Basal ganglia (L)	0.5 (-2.1, 1.7)	0.5 (-2.2, 1.8)	0 (-0.1, 0.1)	0.766
Basal ganglia (R)	0 (-2.5, 0.4)	0.1 (-2.2, 1.3)	-0.3 (-0.7, 0.2)	0.172†
Central region (L)	-0.5 (-2.0, 2.2)	-0.5 (-1.2, 2.6)	-0.2 (-0.8, 0)	0.188†
Central region (R)	-0.8 (-2.3, 0.3)	-0.5 (-2.2, 1.1)	-0.2 (-0.7, 0.4)	0.406
Cingulate & paracingulate gyri (L)	-0.1 (-1.4, 1.2)	0.1 (-0.8, 1.5)	-0.3 (-0.5, 0.3)	0.438
Cingulate & paracingulate gyri (R)	0.4 (-2.2, 0.8)	-1.6 (-2.5, 0.4)	-0.3 (-0.7, 0)	0.250
Frontal lobe (L)	-0.6 (-1.4, 2.8)	0.4 (-0.9, 2.5)	-0.9 (-1.0, -0.5)	0.008†
Frontal lobe (R)	-1.3 (-1.7, 0.3)	-0.8 (-1.2, 1.0)	-0.5 (-0.7, -0.3)	0.094†
Occipital lobe (L)	0.7 (-0.8, 1.9)	1.1 (-0.1, 2.0)	-0.5 (-0.7, -0.63)	0.109†
Occipital lobe (R)	0.3 (0, 1.8)	1.0 (0.6, 1.9)	-0.6 (-0.7, -0.5)	0.078†
Parietal lobe (L)	-0.4 (-0.9, 2.0)	0.1 (-0.2, 1.5)	0 (-0.2, 0.3)	0.945
Parietal lobe (R)	-0.1 (-0.6, 1.4)	0.6 (-0.5, 2.0)	-0.2 (-1.2, 0.1)	0.313
Temporal lobe (L)	0.1 (-0.5, 1.8)	0.2 (0, 1.4)	-0.3 (-0.8, 0.4)	0.590
Temporal lobe (R)	-0.4 (-0.4, 1.5)	0.9 (-0.1, 1.5)	-0.3 (-1.3, 0.3)	0.320

^*by Wilcoxon Sign-rank test for paired data.

L = left; R = right, M = month; SD = standard deviation.

^†Great response: defined as the P<0.2.