Figure 3.
Effects of 5×10-5 mol/L coriaria lactone (CL) on cell cycle of microglia cultured in vitro at different time points as measured by flow cytometry. (A) 0 h (control); (B) 1 h; (C) 2 h; (D) 4 h; (E) 8 h; (F) 24 h; (G) Effects of 5×10-5 mol/L CL on cell cycle of microglia purified and cultured in vitro at different time points. Compared with the control group, the percentage of cells in G0/G1 phase was significantly lower in each group (P < 0.01), but the percentage of cells in S phase was significantly higher (P < 0.05), especially at 1 h of treatment. The percentage of cells in G2/M phase was significantly higher than that in the control group (P < 0.01), especially at 2 h of treatment.