MiR-129-5p expression correlates negatively with malignant degrees of glioma. A. CGGA database showing reduced miR-129-5p expression in high-grade glioma tissues compared with that in low-grade glioma tissues. (***P<0.001). B. The expression of miR-129-5p in nine non-tumor brain tissues (NBTs) and seventeen glioblastoma (GBM) tissues was measured by real-time PCR, miR-129-5p levels in NBTs were indeed higher than in GBM specimens. (***P<0.001). C. The expression of miR-129-5p in normal human astrocytes (NHAs) and six glioma cell lines: U118, LN229, H4, A172, U87 and U251.