Figure 1.

Effect of EPL on cardiac function and ECG wave forms in STZ-isoproterenol challenged rats. All groups are diabetic, where ISO: Isoproterenol; EPL: Eplerenone; Wort: wortmannin; Wort + EPL: wortmanin + Eplerenone. Data were expressed as the mean ± S.E.M. Significance was determined by one-way ANOVA (Analysis of variance) followed by the Bonferroni’s post hoc test: *P<0.05, **P<0.01 as compared to Diabetic ISO; ###P<0.001 as compared to diabetic control; $P<0.001 as compared to eplerenone.