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Effect of EPL on histopathology in STZ-isoproterenol challenged rats. A. Diabetic control. B. Diabetic Isoproterenol. C. Diabetic Isoproterenol + Eplerenone. D. Diabetic Isoproterenol + wortmannin. E. Diabetic Isoproterenol + Eplerenone + wortmanin. The red arrows indicate the myonecrosis and the white arrows indicates the appearance of automatic structures in the myocytes.
