Table I.
Parameters | Total, n | Patients, n (%) |
---|---|---|
Age at diagnosis | 493 | |
≤51 years | 279 (56.6) | |
>51 years | 214 (43.4) | |
Menopausal status | 493 | |
Pre-menopause | 268 (54.4) | |
Post-menopause | 225 (45.6) | |
Tumor size | 493 | |
≤2.0 cm | 325 (65.9) | |
>2.0, <5.0 cm | 146 (29.6) | |
≥5.0 cm | 22 (4.5) | |
Tumor type | 492 | |
Ductal carcinoma | 455 (92.5) | |
Lobular carcinoma | 11 (2.2) | |
Mucinous carcinoma | 9 (1.8) | |
Others | 17 (3.5) | |
Histological grade | 492 | |
G1 | 83 (16.9) | |
G2 | 367 (74.6) | |
G3 | 42 (8.5) | |
TNM stage | 493 | |
I–II | 364 (73.8) | |
III–IV | 129 (26.2) | |
Lymph node metastasis | 493 | |
No | 268 (54.4) | |
Yes | 225 (45.6) | |
p53 | 397 | |
Negative | 166 (41.8) | |
Positive | 231 (58.2) | |
BRCA1 | 396 | |
Negative | 102 (25.8) | |
Positive | 294 (74.2) | |
Chemotherapy regimen | 386 | |
CAF/CEF | 291 (75.4) | |
CAF/CEF+T | 95 (24.6) |
CAF/CEF, cyclophosphamide/doxorubicin or epirubicin/5-fluorouracil; CAF/CEF + T, CAF/CEF+ docetaxel; TNM, tumor-node-metastasis; BRCA1, breast cancer susceptibility gene 1.