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. 2018 Oct 2;9:1106. doi: 10.3389/fphar.2018.01106

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Copyright © 2018 Wang, Yang, Zhang, Wang, Zheng, Li, Liu, Pan, Li, Huang, Zhang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Potential genes involved in the chemosensitizing effects of ADQ against breast cancer. (A,B) The venn analysis showed the crosstalk of DEGs in ADQ and datasets GSE5764/GSE87455 of breast cancer patients before and after chemotherapy; (C) CAV1 was the key target with the largest node size according to “Degree” in the node size mapping; (D) The PPI of hub targets involved in the chemosensitizing effects of ADQ. The blue triangle nodes represent ADQ herbs, and the red rectangle nodes represent the 22 hub targets.