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. 2018 Aug 29;16(5):6003–6012. doi: 10.3892/ol.2018.9371

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Figure 2. — Differences in somatic variants in HCC and BTC. (A) Number of genes mutated in HCC and BTC. (B) The percentage of gene harboring novel variants in the two types of cancer. In HCC samples, 83.2% of the mutated genes harbored novel variants, which was significantly higher than that in BTC samples (65.9%, binomial P<0.01). (C) The SNVs in HCC and BTC. SNVs in the two types of cancer share similar alteration signatures except for T>C, which more frequently occurred in HCC (binomial P<0.05). HCC, hepatocellular carcinoma; BTC, biliary tract cancer; SNVs, single nucleotide variants; CNVs, copy number variants.