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. 2018 Sep 6;16(5):6081–6088. doi: 10.3892/ol.2018.9411

Figure 4.

Figure 4.

The role of TM4SF1 in the proliferation, migration and invasion of gastric cancer cells. (A) TM4SF1 knockdown reduced GC cell proliferation, while TM4SF1 upregulation increased GC cell proliferation. (B) TM4SF1 knockdown reduced GC cell invasion, while TM4SF1 upregulation increased GC cell invasion. (C) TM4SF1 knockdown resulted in reduced GC cell migration, while TM4SF1 upregulation increased GC cell migration. Each column is presented as the means of three separate experiments. *P<0.05, **P<0.01 and ***P<0.001. TM4SF1, transmembrane-4 L6 family member 1; siTM4SF1, cells transfected with TM4SF1 siRNA; control, cells transfected with blank vectors; siTM4SF1+TM4SF1, cells transfected with TM4SF1 siRNA and the TM4SF1-expressing plasmid.