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Effect of gimeracil and oteracil on the growth inhibitory effect of 5-FU in MDA468 and MDA468/FU cells. (A and B) Cells were seeded into 96-well plates and treated with various concentrations of 5-FU with or without (A) gimeracil (100 µM) or (B) oteracil (1 mM) for one week. The cell viability was then determined. Each point represents the mean ± standard deviation (n=4). 5-FU, 5-fluorouracil.
